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The JAK1 Inhibitor Upadacitinib Has No Effect on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol: A Study in Healthy Female Subjects

Upadacitinib is a novel selective oral Janus kinase 1 (JAK) inhibitor being developed for treatment of several inflammatory diseases. Oral contraceptives are anticipated to be a common concomitant medication in the target patient populations. This study was designed to evaluate the effect of multipl...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Mohamed, Mohamed‐Eslam F., Trueman, Sheryl, Feng, Tian, Friedman, Alan, Othman, Ahmed A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587524/
https://ncbi.nlm.nih.gov/pubmed/30500075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1350
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