Pharmacokinetics of renally excreted drug dexpramipexole in subjects with impaired renal function

This phase I, open-label, single-dose study evaluated the pharmacokinetics, safety, and tolerability of renally excreted drug dexpramipexole in subjects with normal and impaired renal function, i.e. mild, moderate, severe renal impairment, or end-stage renal disease (ESRD) requiring hemodialysis whe...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: He, Ping, Kerr, Doug, Marbury, Thomas, Ries, Daniel, Farwell, Wildon, Stecher, Scott, Dong, Yingwen, Wei, Dong, Rogge, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Special Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241030/
https://ncbi.nlm.nih.gov/pubmed/24965504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.353
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