Enhancement of SMN protein levels in a mouse model of spinal muscular atrophy using novel drug-like compounds

Por Cherry, Jonathan J, Osman, Erkan Y, Evans, Matthew C, Choi, Sungwoon, Xing, Xuechao, Cuny, Gregory D, Glicksman, Marcie A, Lorson, Christian L, Androphy, Elliot J
Publicado em 2013

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin

Por Nass, Nada M., Farooque, Sannia, Hind, Charlotte, Wand, Matthew E., Randall, Christopher P., Sutton, J. Mark, Seipke, Ryan F., Rayner, Christopher M., O’Neill, Alex J.
Publicado no Sci Rep (2017)

Homeostatic Imbalance and Colon Cancer: The Dynamic Epigenetic Interplay of Inflammation, Environmental Toxins, and Chemopreventive Plant Compounds

Por Sokolosky, Melissa L., Wargovich, Michael J.
Publicado em 2012

The Development of New Therapies for Human Herpesvirus 6

Por Prichard, Mark N., Whitley, Richard J.
Publicado no Curr Opin Virol (2014)

Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds

Por Rogerio, Kamilla Rodrigues, Carvalho, Leonardo J M, Domingues, Luiza Helena Pinto, Neves, Bruno Junior, Moreira, José Teófilo, Castro, Rosane Nora, Bianco, Cesare, Daniel-Ribeiro, Claudio Tadeu, Andrade, Carolina Horta, Graebin, Cedric Stephan
Publicado no Mem Inst Oswaldo Cruz (2018)

Coenzyme Q10 deficiency due to a COQ4 gene defect causes childhood-onset spinocerebellar ataxia and stroke-like episodes

Por Bosch, Annet M., Kamsteeg, Erik-Jan, Rodenburg, Richard J., van Deutekom, Arend W., Buis, Dennis R., Engelen, Marc, Cobben, Jan-Maarten
Publicado no Mol Genet Metab Rep (2018)

Pathologic Variants of the Mitochondrial Phosphate Carrier SLC25A3: Two New Patients and Expansion...

Por Bhoj, E. J., Li, M., Ahrens-Nicklas, R., Pyle, L. C., Wang, J., Zhang, V. W., Clarke, C., Wong, L. J., Sondheimer, N., Ficicioglu, C., Yudkoff, M.
Publicado no JIMD Rep (2015)

First determination of the $${\rho }$$ ρ parameter at $${\sqrt{s} = 13}$$ s=13 TeV: probing the existence of a colourless C-odd three-gluon compound state

Por G. Antchev, P. Aspell, I. Atanassov, V. Avati, J. Baechler, C. Baldenegro Barrera, V. Berardi, M. Berretti, E. Bossini, U. Bottigli, M. Bozzo, R. Bruce, H. Burkhardt, F. S. Cafagna, M. G. Catanesi, M. Csanád, T. Csörgő, M. Deile, F. De Leonardis, A. D’Orazio, M. Doubek, D. Druzhkin, K. Eggert, V. Eremin, F. Ferro, A. Fiergolski, F. Garcia, H. Garcia Morales, V. Georgiev, S. Giani, L. Grzanka, J. Hammerbauer, J. Heino, P. Helander, T. Isidori, V. Ivanchenko, M. Janda, A. Karev, J. Kašpar, J. Kopal, V. Kundrát, S. Lami, G. Latino, R. Lauhakangas, R. Linhart, C. Lindsey, M. V. Lokajíček, L. Losurdo, M. Lo Vetere, F. Lucas Rodríguez, M. Macrí, M. Malawski, A. Mereghetti, N. Minafra, S. Minutoli, D. Mirarchi, T. Naaranoja, F. Nemes, H. Niewiadomski, T. Novák, E. Oliveri, F. Oljemark, M. Oriunno, K. Österberg, P. Palazzi, V. Passaro, Z. Peroutka, J. Procházka, M. Quinto, E. Radermacher, E. Radicioni, F. Ravotti, S. Redaelli, E. Robutti, C. Royon, G. Ruggiero, H. Saarikko, B. Salvachua, A. Scribano, J. Siroky, J. Smajek, W. Snoeys, R. Stefanovitch, J. Sziklai, C. Taylor, E. Tcherniaev, N. Turini, V. Vacek, G. Valentino, J. Welti, J. Wenninger, J. Williams, P. Wyszkowski, J. Zich, K. Zielinski
Publicado em 2019-09-01

Inhibitors of SARS-CoV-2 PLpro

Por Dale J. Calleja, Dale J. Calleja, Guillaume Lessene, Guillaume Lessene, Guillaume Lessene, David Komander, David Komander
Publicado em 2022-04-01

Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.

Por Féthière, J., Tsuda, Y., Coulombe, R., Konishi, Y., Cygler, M.
Publicado em 1996

Case for a U(1)_{π} Quantum Spin Liquid Ground State in the Dipole-Octupole Pyrochlore Ce_{2}Zr_{2}O_{7}

Por E. M. Smith, O. Benton, D. R. Yahne, B. Placke, R. Schäfer, J. Gaudet, J. Dudemaine, A. Fitterman, J. Beare, A. R. Wildes, S. Bhattacharya, T. DeLazzer, C. R. C. Buhariwalla, N. P. Butch, R. Movshovich, J. D. Garrett, C. A. Marjerrison, J. P. Clancy, E. Kermarrec, G. M. Luke, A. D. Bianchi, K. A. Ross, B. D. Gaulin
Publicado em 2022-04-01

A Visible Light-Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluorospirocyclic ORL-1 Antagonist()

Por Douglas, James J., Albright, Haley, Sevrin, Martin J., Cole, Kevin P., Stephenson, Corey R. J.
Publicado no Angew Chem Int Ed Engl (2015)

... TRPV6 compound heterozygous variants result in impaired placental calcium transport and severe...

Por Burren, Christine P., Caswell, Richard, Castle, Bruce, Welch, C. Ross, Hilliard, Tom N., Smithson, Sarah F., Ellard, Sian
Publicado no Am J Med Genet A (2018)

Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development

Por van Westen, Gerard J. P., Wegner, Jörg K., Geluykens, Peggy, Kwanten, Leen, Vereycken, Inge, Peeters, Anik, IJzerman, Adriaan P., van Vlijmen, Herman W. T., Bender, Andreas
Publicado em 2011

An integrative “omics” approach identifies new candidate genes to impact aroma volatiles in peach fruit

Por Sánchez, Gerardo, Venegas-Calerón, Mónica, Salas, Joaquín J, Monforte, Antonio, Badenes, María L, Granell, Antonio
Publicado em 2013

Synthesis of New Apoptosis-Inducing Iminophosphorane Organogold(III) Complexes and Study of Their Interactions with Biomolecular Targets

Por Shaik, Neha, Martínez, Alberto, Augustin, Idline, Giovinazzo, Hugh, Varela-Ramírez, Armando, Sanaú, Mercedes, Aguilera, Renato J., Contel, María
Publicado em 2009

Identification and design of novel small molecule inhibitors against MERS-CoV papain-like protease via high-throughput screening and molecular modeling

Por Lee, Hyun, Ren, Jinhong, Pesavento, Russell P., Ojeda, Isabel, Rice, Amy J., Lv, Haining, Kwon, Youngjin, Johnson, Michael E.
Publicado no Bioorg Med Chem (2019)

Cheminformatics Analysis of Assertions Mined from Literature that Describe Drug-Induced Liver Injury in Different Species

Por Fourches, D., Barnes, J. C., Day, N. C., Bradley, P., Reed, J.Z., Tropsha, A.
Publicado em 2010

EFFECT OF SODIUM MONOFLUOROACETATE ON THE MULTIPLICATION OF INFLUENZA VIRUSES, MUMPS VIRUS, AND PNEUMONIA VIRUS OF MICE (PVM)

Por Mogabgab, William J., Horsfall, Frank L.
Publicado em 1952

ON THE INFLUENCE OF ACID GROUPS ON THE SEROLOGICAL SPECIFICITY OF AZOPROTEINS

Por Landsteiner, K., van der Scheer, J.
Publicado em 1927