Resultados da pesquisa - (((( j da comas juan nieves ) OR ( j a claims can newts ))) OR ( j i computer viruses ns1 ))*

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Independent-Trajectories Thermodynamic-Integration Free-Energy Changes for Biomolecular Systems: Determinants of H5N1 Avian Influenza Virus Neuraminidase Inhibition by Peramivir

Por Lawrenz, Morgan, Baron, Riccardo, McCammon, J. Andrew
Publicado em 2009

“... 19% underestimation to a 29% overestimation of the experimental reference value (−62.2 ± 1.8 kJ mol...”
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Illustrating and homology modeling the proteins of the Zika virus

Por Ekins, Sean, Liebler, John, Neves, Bruno J., Lewis, Warren G., Coffee, Megan, Bienstock, Rachelle, Southan, Christopher, Andrade, Carolina H.
Publicado no F1000Res (2016)

“.... We now describe preliminary homology models created for NS5, FtsJ, NS4B, NS4A, HELICc, DEXDc...”
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Distinctive Pattern of Sequence Polymorphism in the NS3 Protein of Hepatitis C Virus Type 1b Reflects Conflicting Evolutionary Pressures

Por Irausquin, Stephanie Jiménez, Hughes, Austin L.
Publicado em 2008

“...Analysis of complete polyprotein-encoding sequences of hepatitis C virus genotype 1b (HCV-1b...”
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Characterization of the Zinc Binding Activity of the Rubella Virus Nonstructural Protease

Por Liu, Xin, Yang, Jenny, Ghazi, A. Mohamad, Frey, Teryl K.
Publicado em 2000

“...The rubella virus (RUB) nonstructural (NS) protein (NSP) ORF encodes a protease that cleaves...”
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Hepatitis C Virus RNA Replication and Virus Particle Assembly Require Specific Dimerization of the NS4A Protein Transmembrane Domain

Por Kohlway, Andrew, Pirakitikulr, Nathan, Barrera, Francisco N., Potapova, Olga, Engelman, Donald M., Pyle, Anna M., Lindenbach, Brett D.
Publicado em 2014

“... caused defects in RNA replication and/or virus assembly. Computational modeling of NS4A TM interactions...”
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Mutations in DNA Binding and Transactivation Domains Affect the Dynamics of Parvovirus NS1 Protein

Por Niskanen, Einari A., Kalliolinna, Olli, Ihalainen, Teemu O., Häkkinen, Milla, Vihinen-Ranta, Maija
Publicado em 2013

Assuntos: “...Virus-Cell Interactions...”
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Structure-based discovery of dengue virus protease inhibitors

Por Tomlinson, Suzanne M., Malmstrom, Robert D., Russo, Andrew, Mueller, Niklaus, Pang, Yuan-Ping, Watowich, Stanley J.
Publicado em 2009

“...Dengue virus belongs to the family Flaviviridae and is a major emerging pathogen for which...”
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Unraveling the structural basis of grazoprevir potency against clinically relevant substitutions in hepatitis C virus NS3/4A protease from genotype 1a

Por Guo, Zhuyan, Black, Stuart, Hu, Yuan, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Curry, Stephanie, Asante-Appiah, Ernest
Publicado no J Biol Chem (2017)

Assuntos: “...Computational Biology...”
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Effect of ATP Binding and Hydrolysis on Dynamics of Canine Parvovirus NS1

Por Niskanen, Einari A., Ihalainen, Teemu O., Kalliolinna, Olli, Häkkinen, Milla M., Vihinen-Ranta, Maija
Publicado em 2010

“...-binding pocket resides in the middle of the modular NS1 protein in a superfamily 3 helicase domain. Here...”
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In silico study on anti-Chikungunya virus activity of hesperetin

Por Oo, Adrian, Hassandarvish, Pouya, Chin, Sek Peng, Lee, Vannajan Sanghiran, Abu Bakar, Sazaly, Zandi, Keivan
Publicado no PeerJ (2016)

Assuntos: “...Computational Biology...”
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Elucidating Influenza Inhibition Pathways via Network Reconstruction

Por Mazza, Arnon, Gat-Viks, Irit, Sharan, Roded
Publicado em 2014

“... to influenza infection in humans, with and without the viral inhibitory protein NS1, revealing its direct...”
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Inhibition of hepatitis C virus replication by single-stranded RNA structural mimics

Por Smolic, Robert, Smolic, Martina, Andorfer, John H, Wu, Catherine H, Smith, Robert M, Wu, George Y
Publicado em 2010

“... genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model...”
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Study on the Behavior of Dengue Viruses during Outbreaks with Reference to Entomological...

Por Basker, Parasuraman, Kolandaswamy, Karumana Gounder
Publicado no Osong Public Health Res Perspect (2015)

“... of the dengue viruses in humans was detected at 15 days, NS1 was identified as a tool for the early diagnosis...”
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Parvovirus B19 Integration into Human CD36+ Erythroid Progenitor Cells

Por Janovitz, Tyler, Wong, Susan, Young, Neal S., Oliveira, Thiago, Falck-Pedersen, Erik
Publicado no Virology (2017)

“... cells (EPCs). Functional similarities between B19V nonstructural protein (NS1), a DNA binding...”
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Recombination in West Nile Virus: minimal contribution to genomic diversity

Por Pickett, Brett E, Lefkowitz, Elliot J
Publicado em 2009

“... taxonomic lineages 2, 1a, and 2 respectively. This one isolated recombinant genome was out of a total of 154...”
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Determination of Hepatitis C Virus Genotype by Direct Sequence Analysis of Products Generated with the Amplicor HCV Test

Por Germer, Jeff J., Rys, Paul N., Thorvilson, Jill N., Persing, David H.
Publicado em 1999

“...Consistent with other members of the family Flaviviridae, hepatitis C virus (HCV) demonstrates a...”
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Computer simulation of ion channel gating: the M(2) channel of influenza A virus in a lipid bilayer.

Por Schweighofer, K J, Pohorille, A
Publicado em 2000

“... phospholipid bilayer, a 1.3-ns trajectory was obtained. It is found that the states involved in the shuttle...”
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Novel Druggable Hot Spots in Avian Influenza Neuraminidase H5N1 Revealed by Computational Solvent Mapping of a Reduced and Representative Receptor Ensemble

Por Landon, Melissa R, Amaro, Rommie E, Baron, Riccardo, Ngan, Chi Ho, Ozonoff, David, Andrew McCammon, J, Vajda, Sandor
Publicado em 2008

“...The influenza virus subtype H5N1 has raised concerns of a possible human pandemic threat because...”
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The Influence of Hepatitis C Virus Genetic Region on Phylogenetic Clustering Analysis

Por Lamoury, François M. J., Jacka, Brendan, Bartlett, Sofia, Bull, Rowena A., Wong, Arthur, Amin, Janaki, Schinkel, Janke, Poon, Art F., Matthews, Gail V., Grebely, Jason, Dore, Gregory J., Applegate, Tanya L.
Publicado no PLoS One (2015)

“... for clustering analysis; NS5B concatenation, the inclusion of reference sequences and removal of HVR1 all...”
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The hepatitis C virus RNA-dependent RNA polymerase directs incoming nucleotides to its active site through magnesium-dependent dynamics within its F motif

Por Ben Ouirane, Kaouther, Boulard, Yves, Bressanelli, Stéphane
Publicado no J Biol Chem (2019)

Assuntos: “...Computational Biology...”
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