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Mutations in DNA Binding and Transactivation Domains Affect the Dynamics of Parvovirus NS1 Protein

The multifunctional replication protein of autonomous parvoviruses, NS1, is vital for viral genome replication and for the control of viral protein production. Two DNA-interacting domains of NS1, the N-terminal and helicase domains, are necessary for these functions. In addition, the N and C termini...

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Main Authors: Niskanen, Einari A., Kalliolinna, Olli, Ihalainen, Teemu O., Häkkinen, Milla, Vihinen-Ranta, Maija
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807334/
https://ncbi.nlm.nih.gov/pubmed/23986577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01678-13
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