Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer

Por Sartore-Bianchi, Andrea, Valtorta, Emanuele, Amatu, Alessio, Veronese, Silvio, Lauricella, Calogero, Bonazzina, Erica, Siravegna, Giulia, Truini, Mauro, Bardelli, Alberto, Siena, Salvatore
Publicado no ESMO Open (2016)

Time since start of first-line therapy as a predictive clinical marker for nintedanib in patients with previously treated non-small cell lung cancer

Por Gaschler-Markefski, Birgit, Sikken, Patricia, Heymach, John V, Gottfried, Maya, Mellemgaard, Anders, Novello, Silvia, Gann, Claudia-Nanette, Barrueco, José, Reck, Martin, Hanna, Nasser H, Kaiser, Rolf
Publicado no ESMO Open (2017)

Tumour-infiltrating lymphocytes are correlated with higher expression levels of PD-1 and PD-L1 in early breast cancer

Por Kitano, Atsuko, Ono, Makiko, Yoshida, Masayuki, Noguchi, Emi, Shimomura, Akihiko, Shimoi, Tatsunori, Kodaira, Makoto, Yunokawa, Mayu, Yonemori, Kan, Shimizu, Chikako, Kinoshita, Takayuki, Fujiwara, Yasuhiro, Tsuda, Hitoshi, Tamura, Kenji
Publicado no ESMO Open (2017)

A consensus on liquid biopsy from the 2016 Chinese Lung Cancer Summit expert panel

Por Wu, Yi-Long, Wang, Chang-Li, Sun, Yan, Liao, Mei-Lin, Guan, Zhong-Zhen, Yang, Zhi-Min, Zhou, Qing-Hua, Lu, Shun, Cheng, Ying, Liu, Xiao-Qing, Zhang, Xu-Chao, Zhou, Caicun, Wang, Jie, Zhou, Qing, Song, Yong, Han, Bao-Hui, Ma, Zhi-Yong, Yang, Fan, Wang, Qun, Chuai, Shao-Kun, Shao, Yang, He, Wei, Zhu, Guanshan, Xiong, Lei, Wang, Jian-Jun, Chen, Ke-Neng, Zhang, Li, Mao, Wei-Min, Ma, Sheng-Lin, Feng, Ji-Feng, Yang, Xue-Ning, Xu, Lin, Chen, Gang, Zhao, Jian, Song, Qi-Bin, SHEN-TU, Yang, Qiao, Gui-Bin, Yu, Ding, Yu, Shi-Ying, Hu, Yi, Chen, Ming, Chen, Gong-Yan, Fan, Yun, Zhang, He-Long, Liang, Jun, Zhu, Guang-Ying, Cui, Jiu-Wei, Yang, Jin-Ji, Zhao, Qiong, Zhao, Ming-Fang, Lu, You, Chang, Jian-Hua, Li, Jun-Ling, Yang, Yue, Hu, Jie, Gu, Chun-Dong, Zhang, Yi-Chen, Zhong, Wen-Zhao
Publicado no ESMO Open (2017)

Safety and activity of IT-139, a ruthenium-based compound, in patients with advanced solid tumours: a first-in-human, open-label, dose-escalation phase I study with expansion cohor...

Por Burris, Howard A, Bakewell, Suzanne, Bendell, Johanna C, Infante, Jeffrey, Jones, Suzanne F, Spigel, David R, Weiss, Glen J, Ramanathan, Ramesh K, Ogden, Angela, Von Hoff, Daniel
Publicado no ESMO Open (2017)

Clinical outcome and molecular characterisation of chemorefractory metastatic colorectal cancer patients with long-term efficacy of regorafenib treatment

Por Martinelli, Erika, Sforza, Vincenzo, Cardone, Claudia, Capasso, Anna, Nappi, Anna, Martini, Giulia, Napolitano, Stefania, Rachiglio, Anna Maria, Normanno, Nicola, Cappabianca, Salvatore, Reginelli, Alfonso, Bisceglie, Maurizio Di, Latiano, Tiziana Pia, Maiello, Evaristo, Orditura, Michele, Vita, Fernando De, Morgillo, Floriana, Ciardiello, Fortunato, Troiani, Teresa
Publicado no ESMO Open (2017)

Phase I study of neoadjuvant chemotherapy with S-1 and oxaliplatin for locally advanced gastric cancer (Neo G-SOX PI)

Por Satake, Hironaga, Miki, Akira, Kondo, Masato, Kotake, Takeshi, Okita, Yoshihiro, Hatachi, Yukimasa, Yasui, Hisateru, Imai, Yukihiro, Ichikawa, Chihiro, Murotani, Kenta, Hashida, Hiroki, Kobayashi, Hiroyuki, Kotaka, Masahito, Kato, Takeshi, Kaihara, Satoshi, Tsuji, Akihito
Publicado no ESMO Open (2017)

Phase III study of gefitinib or pemetrexed with carboplatin in EGFR-mutated advanced lung adenocarcinoma

Por Patil, Vijay Maruti, Noronha, Vanita, Joshi, Amit, Choughule, Anuradha Bharat, Bhattacharjee, Atanu, Kumar, Rajiv, Goud, Supriya, More, Sucheta, Ramaswamy, Anant, Karpe, Ashay, Pande, Nikhil, Chandrasekharan, Arun, Goel, Alok, Talreja, Vikas, Mahajan, Abhishek, Janu, Amit, Purandare, Nilendu, Prabhash, Kumar
Publicado no ESMO Open (2017)

Recent developments and translational aspects in targeted therapy for metastatic breast cancer

Por Marhold, Maximilian, Bartsch, Rupert, Zielinski, Christoph
Publicado no ESMO Open (2016)

KRAS-driven lung adenocarcinoma: combined DDR1/Notch inhibition as an effective therapy

Por Ambrogio, Chiara, Nadal, Ernest, Villanueva, Alberto, Gómez-López, Gonzalo, Cash, Timothy P, Barbacid, Mariano, Santamaría, David
Publicado no ESMO Open (2016)

ESMO gave me a chance to help make a difference: a personal reflection on the occasion of receiving the 2015 ESMO Award

Por Cherny, Nathan I
Publicado no ESMO Open (2016)

CECOG educational illustrations: the blood–brain barrier and its relevance for targeted cancer therapies and immuno-oncology

Por Preusser, Matthias, Berghoff, Anna S, Thallinger, Christiane, Zielinski, Christoph
Publicado no ESMO Open (2017)

Recent advances in the biology and treatment of brain metastases of non-small cell lung cancer: summary of a multidisciplinary roundtable discussion

Por Preusser, Matthias, Winkler, Frank, Valiente, Manuel, Manegold, Christian, Moyal, Elizabeth, Widhalm, Georg, Tonn, Jörg-Christian, Zielinski, Christoph
Publicado no ESMO Open (2018)

Health-related quality of life in a randomised phase III study of gemcitabine plus S-1, S-1 alone and gemcitabine alone for locally advanced or metastatic pancreatic cancer: GEST s...

Por Hagiwara, Yasuhiro, Ohashi, Yasuo, Okusaka, Takuji, Ueno, Hideki, Ioka, Tatsuya, Boku, Narikazu, Egawa, Shinichi, Hatori, Takashi, Furuse, Junji, Mizumoto, Kazuhiro, Ohkawa, Shinichi, Yamaguchi, Taketo, Yamao, Kenji, Funakoshi, Akihiro, Cheng, Ann-Lii, Kihara, Kiyohiro, Sato, Atsushi, Tanaka, Masao
Publicado no ESMO Open (2017)

Results of the safety run-in part of the METAL (METformin in Advanced Lung cancer) study: a multicentre, open-label phase I–II study of metformin with erlotinib in second-line ther...

Por Morgillo, Floriana, Fasano, Morena, Della Corte, Carminia Maria, Sasso, Ferdinando Carlo, Papaccio, Federica, Viscardi, Giuseppe, Esposito, Giovanna, Di Liello, Raimondo, Normanno, Nicola, Capuano, Annalisa, Berrino, Liberato, Vicidomini, Giovanni, Fiorelli, Alfonso, Santini, Mario, Ciardiello, Fortunato
Publicado no ESMO Open (2017)

S-1 and oxaliplatin (SOX) plus bevacizumab versus mFOLFOX6 plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer: updated overall survival analyse...

Por Baba, Hideo, Yamada, Yasuhide, Takahari, Daisuke, Matsumoto, Hiroshi, Yoshida, Kazuhiro, Nakamura, Masato, Yoshida, Motoki, Iwamoto, Shigeyoshi, Shimada, Ken, Komatsu, Yoshito, Sasaki, Yasutsuna, Satoh, Taroh, Takahashi, Keiichi, Mishima, Hideyuki, Muro, Kei, Watanabe, Masahiko, Sakata, Yuh, Morita, Satoshi, Shimada, Yasuhiro, Sugihara, Kenichi
Publicado no ESMO Open (2017)

Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate

Por Ree, Anne Hansen, Russnes, Hege G, Heinrich, Daniel, Dueland, Svein, Boye, Kjetil, Nygaard, Vigdis, Silwal-Pandit, Laxmi, Østrup, Olga, Hovig, Eivind, Nygaard, Vegard, Rødland, Einar A, Nakken, Sigve, Øien, Janne T, Johansen, Christin, Bergheim, Inger R, Skarpeteig, Veronica, Sathermugathevan, Menaka, Sauer, Torill, Lund-Iversen, Marius, Beiske, Klaus, Nasser, Salah, Julsrud, Lars, Reisse, Claudius H, Ruud, Espen A, Flørenes, Vivi Ann, Hagene, Kirsten T, Aas, Eline, Lurås, Hilde, Johnsen-Soriano, Siv, Geitvik, Gry A, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Mælandsmo, Gunhild M, Flatmark, Kjersti
Publicado no ESMO Open (2017)

The European Cancer Patient’s Bill of Rights, update and implementation 2016

Por Højgaard, Liselotte, Löwenberg, Bob, Selby, Peter, Lawler, Mark, Banks, Ian, Law, Kate, Albreht, Tit, Armand, Jean-Pierre, Barbacid, Mariano, Barzach, Michèle, Bergh, Jonas, Cameron, David, Conte, Pierfranco, de Braud, Filippo, de Gramont, Aimery, De Lorenzo, Francesco, Diehl, Volker, Diler, Sarper, Erdem, Sema, Geissler, Jan, Gore-Booth, Jola, Henning, Geoffrey, Horgan, Denis, Jassem, Jacek, Johnson, Peter, Kaasa, Stein, Kapitein, Peter, Karjalainen, Sakari, Kelly, Joan, Kienesberger, Anita, La Vecchia, Carlo, Lacombe, Denis, Lindahl, Tomas, Luzzatto, Lucio, Malby, Rebecca, Mastris, Ken, Meunier, Françoise, Murphy, Martin, Naredi, Peter, Nurse, Paul, Oliver, Kathy, Pearce, Jonathan, Pelouchov, Jana, Piccart, Martine, Pinedo, Bob, Spurrier-Bernard, Gilly, Sullivan, Richard, Tabernero, Josep, Van de Velde, Cornelis, van Herk, Bert, Vedsted, Peter, Waldmann, Anita, Weller, David, Wilking, Nils, Wilson, Roger, Yared, Wendy, Zielinski, Christoph, zur Hausen, Harald, Le Chevalier, Thierry, Johnston, Patrick
Publicado no ESMO Open (2017)

Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy

Por Milani, Andrea, Kristeleit, Rebecca, McCormack, Mary, Raja, Fharat, Luvero, Daniela, Widschwendter, Martin, MacDonald, Nicola, Mould, Tim, Olatain, Adeola, Hackshaw, Allan, Ledermann, Jonathan A
Publicado no ESMO Open (2017)

Cancer and liver cirrhosis: implications on prognosis and management

Por Pinter, Matthias, Trauner, Michael, Peck-Radosavljevic, Markus, Sieghart, Wolfgang
Publicado no ESMO Open (2016)