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Highly Diastereoselective Addition of a Racemic b-Alanine Enolate Derivative to Electrophiles

b-Alanine, an inexpensive b-amino acid, was convertedinto the 2-phenylperhydropyrimidin-4-one derivative (1), which canbe alkylated with high diastereoselectivity via the corresponding enolate.The high stereoselectivity observed for the reaction of (1)-Liwith electrophiles seems to be due to steric...

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Detalhes bibliográficos
Publicado no:Journal of the Mexican Chemical Society
Main Authors: Jaime Escalante, Ana Lilia Hernández, Eusebio Juaristi
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedad Química de México 2001
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Acesso em linha:https://www.redalyc.org/articulo.oa?id=47545409
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