SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation

Notch receptors and their ligands play important roles in both normal animal development and pathogenesis. We show here that the F-box/WD40 repeat protein SEL-10 negatively regulates Notch receptor activity by targeting the intracellular domain of Notch receptors for ubiquitin-mediated protein degra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Guangyu, Lyapina, Svetlana, Das, Indranil, Li, Jinhe, Gurney, Mark, Pauley, Adele, Chui, Inca, Deshaies, Raymond J., Kitajewski, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99913/
https://ncbi.nlm.nih.gov/pubmed/11585921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7403-7415.2001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados