SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation
Notch receptors and their ligands play important roles in both normal animal development and pathogenesis. We show here that the F-box/WD40 repeat protein SEL-10 negatively regulates Notch receptor activity by targeting the intracellular domain of Notch receptors for ubiquitin-mediated protein degra...
Zapisane w:
| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2001
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11585921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.21.7403-7415.2001 |
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