SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation

Notch receptors and their ligands play important roles in both normal animal development and pathogenesis. We show here that the F-box/WD40 repeat protein SEL-10 negatively regulates Notch receptor activity by targeting the intracellular domain of Notch receptors for ubiquitin-mediated protein degra...

Description complète

Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Wu, Guangyu, Lyapina, Svetlana, Das, Indranil, Li, Jinhe, Gurney, Mark, Pauley, Adele, Chui, Inca, Deshaies, Raymond J., Kitajewski, Jan
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2001
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11585921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.21.7403-7415.2001
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!