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Repair of DNA Strand Breaks by the Overlapping Functions of Lesion-Specific and Non-Lesion-Specific DNA 3′ Phosphatases
In Saccharomyces cerevisiae, the apurinic/apyrimidinic (AP) endonucleases Apn1 and Apn2 act as alternative pathways for the removal of various 3′-terminal blocking lesions from DNA strand breaks and in the repair of abasic sites, which both result from oxidative DNA damage. Here we demonstrate that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99894/ https://ncbi.nlm.nih.gov/pubmed/11585902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.21.7191-7198.2001 |
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