DNA Substrate Dependence of p53-Mediated Regulation of Double-Strand Break Repair

DNA double-strand breaks (DSBs) arise spontaneously after the conversion of DNA adducts or single-strand breaks by DNA repair or replication and can be introduced experimentally by expression of specific endonucleases. Correct repair of DSBs is central to the maintenance of genomic integrity in mamm...

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Bibliographic Details
Main Authors: Akyüz, Nuray, Boehden, Gisa S., Süsse, Silke, Rimek, Andreas, Preuss, Ute, Scheidtmann, Karl-Heinz, Wiesmüller, Lisa
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC134001/
https://ncbi.nlm.nih.gov/pubmed/12167722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6306-6317.2002
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