Arsenic Trioxide Is a Potent Inhibitor of the Interaction of SMRT Corepressor with Its Transcription Factor Partners, Including the PML-Retinoic Acid Receptor α Oncoprotein Found in Human Acute Promyelocytic Leukemia

The SMRT corepressor complex participates in transcriptional repression by a diverse array of vertebrate transcription factors. The ability to recruit SMRT appears to play a crucial role in leukemogenesis by the PML-retinoic acid receptor α (RARα) oncoprotein, an aberrant nuclear hormone receptor im...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Hong, Suk-Hyun, Yang, Zhihong, Privalsky, Martin L.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2001
Subjects:	Transcriptional Regulation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99892/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11585900/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.21.7172-7182.2001
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