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Membrane Raft-Dependent Regulation of Phospholipase Cγ-1 Activation in T Lymphocytes

Numerous signaling molecules associate with lipid rafts, either constitutively or after engagement of surface receptors. One such molecule, phospholipase Cγ-1 (PLCγ1), translocates from the cytosol to lipid rafts during T-cell receptor (TCR) signaling. To investigate the role played by lipid rafts i...

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Autors principals: Verí, Maria-Concetta, DeBell, Karen E., Seminario, Maria-Cristina, DiBaldassarre, Angela, Reischl, Ilona, Rawat, Rashmi, Graham, Laurie, Noviello, Cristiana, Rellahan, Barbara L., Miscia, Sebastiano, Wange, Ronald L., Bonvini, Ezio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99870/
https://ncbi.nlm.nih.gov/pubmed/11564877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6939-6950.2001
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