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Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions
Human monocyte-derived DCs (moDCs) and circulating conventional DCs coexpress activating (CD32a) and inhibitory (CD32b) isoforms of IgG Fcγ receptor (FcγR) II (CD32). The balance between these divergent receptors establishes a threshold of DC activation and enables immune complexes to mediate opposi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201664/ https://ncbi.nlm.nih.gov/pubmed/16167082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24772 |
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