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The role of IgG Fc receptors in antibody-dependent enhancement

Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non-neutralizing antiviral antibodies. In vitro modelling of ADE has attributed enhanced pathogenesis to Fcγ receptor (FcγR)-med...

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Bibliographic Details
Published in:Nat Rev Immunol
Main Authors: Bournazos, Stylianos, Gupta, Aaron, Ravetch, Jeffrey V.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418887/
https://ncbi.nlm.nih.gov/pubmed/32782358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-00410-0
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