A carregar...
Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity
The effector activity of antibodies is dependent on engagement with Fcγ receptors (FcγRs) and activation of the associated intracellular signaling pathways. Preclinical evaluation of therapeutic humanized or chimeric mAbs to study the interactions of their Fc regions with FcγRs is hampered by substa...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904629/ https://ncbi.nlm.nih.gov/pubmed/24401277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72676 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|