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Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity
IgG antibodies are glycoproteins containing a branched sugar moiety attached to the asparagine 297 residue in the antibody constant region (Fc). This glycan is essential for maintaining a functional Fc structure, which is a prerequisite for antibody-mediated effector functions, such as the interacti...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895967/ https://ncbi.nlm.nih.gov/pubmed/17485663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702936104 |
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