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FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo
Cellular Fcγ receptors are essential for IgG-dependent effector functions in vivo. There is convincing evidence that selective activating Fcγ receptors are responsible for the activity of individual IgG subclasses. Thus, IgG1 activity is absent in FcγRIII-deficient mice, and several studies suggest...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984189/ https://ncbi.nlm.nih.gov/pubmed/20974962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014515107 |
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