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FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo

Cellular Fcγ receptors are essential for IgG-dependent effector functions in vivo. There is convincing evidence that selective activating Fcγ receptors are responsible for the activity of individual IgG subclasses. Thus, IgG1 activity is absent in FcγRIII-deficient mice, and several studies suggest...

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Hlavní autoři: Nimmerjahn, Falk, Lux, Anja, Albert, Heike, Woigk, Melissa, Lehmann, Christian, Dudziak, Diana, Smith, Patrick, Ravetch, Jeffrey V.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984189/
https://ncbi.nlm.nih.gov/pubmed/20974962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014515107
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