In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner

IgG antibodies are potent inducers of proinflammatory responses. During autoimmune diseases such as arthritis and systemic lupus erythematosus, IgG autoantibodies are responsible for the chronic inflammation and destruction of healthy tissues by cross-linking Fc receptors on innate immune effector c...

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Detaylı Bibliyografya
Asıl Yazarlar: Albert, Heike, Collin, Mattias, Dudziak, Diana, Ravetch, Jeffrey V., Nimmerjahn, Falk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567483/
https://ncbi.nlm.nih.gov/pubmed/18815375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808248105
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