Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

Mechanisms controlling the disassembly of ezrin/radixin/moesin (ERM) proteins, which link the cytoskeleton to the plasma membrane, are incompletely understood. In lymphocytes, chemokine (e.g., SDF-1) stimulation inactivates ERM proteins, causing their release from the plasma membrane and dephosphory...

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Detalhes bibliográficos
Main Authors: Hao, Jian-Jiang, Liu, Yin, Kruhlak, Michael, Debell, Karen E., Rellahan, Barbara L., Shaw, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646552/
https://ncbi.nlm.nih.gov/pubmed/19204146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807047
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