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LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

ERM (ezrin-radixin-moesin) proteins mediate linkage of actin cytoskeleton to plasma membrane in many cells. ERM activity is regulated in part by phosphorylation at a C-terminal threonine, but the identity of ERM kinases is unknown in lymphocytes and incompletely defined in other mammalian cells. Our...

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Detalhes bibliográficos
Main Authors: Belkina, Natalya V., Liu, Yin, Hao, Jian-Jiang, Karasuyama, Hajime, Shaw, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660762/
https://ncbi.nlm.nih.gov/pubmed/19255442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805963106
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