Activation of Moesin, a Protein That Links Actin Cytoskeleton to the Plasma Membrane, Occurs by Phosphatidylinositol 4,5-bisphosphate (PIP2) Binding Sequentially to Two Sites and Releasing an Autoinhibitory Linker

Many cellular processes depend on ERM (ezrin, moesin, and radixin) proteins mediating regulated linkage between plasma membrane and actin cytoskeleton. Although conformational activation of the ERM protein is mediated by the membrane PIP2, the known properties of the two described PIP2-binding sites...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ben-Aissa, Khadija, Patino-Lopez, Genaro, Belkina, Natalya V., Maniti, Ofelia, Rosales, Tilman, Hao, Jian-Jiang, Kruhlak, Michael J., Knutson, Jay R., Picart, Catherine, Shaw, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351316/
https://ncbi.nlm.nih.gov/pubmed/22433855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304881
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados