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Phosphatidylinositol 4,5-bisphosphate (PIP(2))-specific AKT1 is oncogenic

The protein kinase AKT1 (v-akt murine thymoma viral oncogene homologue 1), also referred to as PKB (protein kinase B), is an essential mediator of the phosphatidylinositol 3-kinase signaling pathway. Elevated activity of AKT1 is common in human cancer. Localization at the plasma membrane, leading to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dannemann, Nadine, Hart, Jonathan Ross, Ueno, Lynn, Vogt, Peter K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862841/
https://ncbi.nlm.nih.gov/pubmed/19876913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25012
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