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Phosphatidylinositol 4,5-bisphosphate (PIP(2))-specific AKT1 is oncogenic
The protein kinase AKT1 (v-akt murine thymoma viral oncogene homologue 1), also referred to as PKB (protein kinase B), is an essential mediator of the phosphatidylinositol 3-kinase signaling pathway. Elevated activity of AKT1 is common in human cancer. Localization at the plasma membrane, leading to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862841/ https://ncbi.nlm.nih.gov/pubmed/19876913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25012 |
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