Antibody to phosphatidylinositol 4,5-bisphosphate inhibits oncogene-induced mitogenesis.

The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to be enhanced in cells transformed by some types of oncogenes and tumor viruses, but it is still unknown whether the breakdown of PIP2 plays a role in oncogene-induced cell proliferation. For examination of this problem,...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fukami, K, Matsuoka, K, Nakanishi, O, Yamakawa, A, Kawai, S, Takenawa, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9057
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