Antibody to phosphatidylinositol 4,5-bisphosphate inhibits oncogene-induced mitogenesis.
The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to be enhanced in cells transformed by some types of oncogenes and tumor viruses, but it is still unknown whether the breakdown of PIP2 plays a role in oncogene-induced cell proliferation. For examination of this problem,...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1988
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9057 |
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