Antibody to phosphatidylinositol 4,5-bisphosphate inhibits oncogene-induced mitogenesis.
The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to be enhanced in cells transformed by some types of oncogenes and tumor viruses, but it is still unknown whether the breakdown of PIP2 plays a role in oncogene-induced cell proliferation. For examination of this problem,...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1988
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9057 |
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