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The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells

The damaged-DNA binding protein DDB consists of two subunits, DDB1 (127 kDa) and DDB2 (48 kDa). Mutations in the DDB2 subunit have been detected in patients suffering from the repair deficiency disease xeroderma pigmentosum (group E). In addition, recent studies suggested a role for DDB2 in global g...

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Autors principals: Nag, Alo, Bondar, Tanya, Shiv, Shalu, Raychaudhuri, Pradip
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99852/
https://ncbi.nlm.nih.gov/pubmed/11564859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6738-6747.2001
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