Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
In human cells, efficient global genomic repair of DNA damage induced by ultraviolet radiation requires the p53 tumor suppressor, but the mechanism has been unclear. The p48 gene is required for expression of an ultraviolet radiation-damaged DNA binding activity and is disrupted by mutations in the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15152/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892649/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.424 |
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