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The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells

The damaged-DNA binding protein DDB consists of two subunits, DDB1 (127 kDa) and DDB2 (48 kDa). Mutations in the DDB2 subunit have been detected in patients suffering from the repair deficiency disease xeroderma pigmentosum (group E). In addition, recent studies suggested a role for DDB2 in global g...

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Hlavní autoři: Nag, Alo, Bondar, Tanya, Shiv, Shalu, Raychaudhuri, Pradip
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC99852/
https://ncbi.nlm.nih.gov/pubmed/11564859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6738-6747.2001
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