Shared Pathways of IκB Kinase-Induced SCF(βTrCP)-Mediated Ubiquitination and Degradation for the NF-κB Precursor p105 and IκBα
p105 (NFKB1) acts in a dual way as a cytoplasmic IκB molecule and as the source of the NF-κB p50 subunit upon processing. p105 can form various heterodimers with other NF-κB subunits, including its own processing product, p50, and these complexes are signal responsive. Signaling through the IκB kina...
Sparad:
| I publikationen: | Mol Cell Biol |
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| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Taylor & Francis
2001
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.4.1024-1035.2001 |
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