Codon Optimization of Gene Fragments Encoding Plasmodium falciparum Merzoite Proteins Enhances DNA Vaccine Protein Expression and Immunogenicity in Mice

In contrast to conventional vaccines, DNA and other subunit vaccines exclusively utilize host cell molecules for transcription and translation of proteins. The adenine plus thymine content of Plasmodium falciparum gene sequences (∼80%) is much greater than that of Homo sapiens (∼59%); consequently,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Narum, David L., Kumar, Sanjai, Rogers, William O., Fuhrmann, Steven R., Liang, Hong, Oakley, Miranda, Taye, Alem, Sim, B. Kim Lee, Hoffman, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98808/
https://ncbi.nlm.nih.gov/pubmed/11705894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.12.7250-7253.2001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker