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A Recombinant Baculovirus-Expressed Plasmodium falciparum Receptor-Binding Domain of Erythrocyte Binding Protein EBA-175 Biologically Mimics Native Protein

EBA-175 of Plasmodium falciparum is a merozoite ligand that binds its receptor glycophorin A on erythrocytes during invasion. The ligand-receptor interaction is dependent on sialic acids as well as the protein backbone of glycophorin A. Region II (RII) of EBA-175 has been defined as the receptor-bin...

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Autors principals: Liang, Hong, Narum, David L., Fuhrmann, Steven R., Luu, Tin, Sim, B. Kim Lee
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97643/
https://ncbi.nlm.nih.gov/pubmed/10816512
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