HLA-A*01-Restricted Cytotoxic T-Lymphocyte Epitope from the Plasmodium falciparum Circumsporozoite Protein

Here, we report the identification of a novel CD8(+) cytotoxic T-lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein (3D7; amino acids 310 to 319 [EPSDKHIKEY]) that is restricted by HLA-A*01 and is recognized by human volunteers immunized with irradiated P. falciparum sporozoite...

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Detalhes bibliográficos
Main Authors: Kumar, Anita, Kumar, Sanjai, Le, Thong P., Southwood, Scott, Sidney, John, Cohen, Joe, Sette, Alessandro, Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98223/
https://ncbi.nlm.nih.gov/pubmed/11254651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2766-2771.2001
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