CD85/LIR-1/ILT2 and CD152 (Cytotoxic T Lymphocyte Antigen 4) Inhibitory Molecules Down-Regulate the Cytolytic Activity of Human CD4(+) T-Cell Clones Specific for Mycobacterium tuberculosis

Antigen-specific cytolytic CD4(+) T lymphocytes control Mycobacterium tuberculosis infection by secreting cytokines and by killing macrophages that have phagocytosed the pathogen. However, lysis of the latter cells promotes microbial dissemination, and other macrophages engulf the released bacteria....

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Merlo, Andrea, Saverino, Daniele, Tenca, Claudya, Grossi, Carlo Enrico, Bruno, Silvia, Ciccone, Ermanno
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.10.6022-6029.2001
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