Crystal structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18

BACKGROUND: Leukocyte Immunoglobulin-like Receptor-1 (LIR-1) and LIR-2 (also known as ILT2 and ILT4 respectively) are highly related cell surface receptors that bind a broad range of class I MHC molecules with low (μM) affinities. Expressed on monocytic cells and macrophages, both molecules transmit...

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Main Authors: Willcox, Benjamin E, Thomas, Leonard M, Chapman, Tara L, Heikema, Astrid P, West, Anthony P, Bjorkman, Pamela J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130215/
https://ncbi.nlm.nih.gov/pubmed/12390682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-2-6
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