Major Histocompatibility Complex (MHC) in Health and Disease

The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually...

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Hlavní autoři:	Shiina, Takashi, Dijkstra, Johannes M., Kulski, Jerzy K.
Médium:	Livro
Jazyk:	Inglês
Vydáno:	MDPI - Multidisciplinary Digital Publishing Institute 2020
Témata:	QH301-705.5 Q1-390 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences HCP5 n/a camels MHC STK19 major histocompatibility complex human papillomavirus (HPV) T-cell receptor T1DGC bottleneck micro-mini-pigs life history computational analysis hepatocellular carcinoma phase Bactrian camel NSDK melanoma antigen autoimmune disease RD selection disease resistance autoimmunity ancestral haplotype Ski complex DXO high-throughput sequencing conservation genetics SVA lncRNA ankylosing spondylitis MHC genes viral peptides competing endogenous RNA (ceRNA) astrogliosis birds long-fragment super haplotype SNP RLR HLA polymorphism 5??3? RNA decay expression 3??5? mRNA turnover orthology long-read sequencing disease association dromedary polyomavirus MHC-II-associated sperm-egg recognition experimental medicine single nucleotide polymorphism (SNP) fish SKIV2L production trait molecular dynamics simulation Macaca fascicularis human endogenous retrovirus (HERV) concerted evolution polymorphism Old World camels MHC polymorphism protocol nonclassical gene duplication microglial reaction human leukocyte antigen-E SKI2W quantitative trait loci (QTL) studies antiviral immunity human immunodeficiency virus (HIV) founder effect giant panda domain movements BK virus promoter-proximal transcriptional pause type 1 diabetes (T1D) RP1 miR1236 KIR synaptic covering swine leukocyte antigen cynomolgus macaque HLA kidney transplantation ?2m knockout mice DOM3Z interferon ? ethnic populations in China ecology KIR–HLA pairs exosomes major histocompatibility complex (MHC) MHC-I-based mother-fetus recognition RNA quality control autoimmune diseases NELF-E haplotype genetic drift evolution nonhuman primate models HLA-B27 PNS/CNS interface risk genes pedigree MHC-I- and MHC-II-dependent inter-individual recognition regulation crested ibis reproductive performance nephropathy cancer nuclear kinase trichohepatoenteric syndrome
On-line přístup:	https://directory.doabooks.org/handle/20.500.12854/52604
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Major Histocompatibility Complex (MHC) in Health and Disease

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