CD85/LIR-1/ILT2 and CD152 (Cytotoxic T Lymphocyte Antigen 4) Inhibitory Molecules Down-Regulate the Cytolytic Activity of Human CD4(+) T-Cell Clones Specific for Mycobacterium tuberculosis

Antigen-specific cytolytic CD4(+) T lymphocytes control Mycobacterium tuberculosis infection by secreting cytokines and by killing macrophages that have phagocytosed the pathogen. However, lysis of the latter cells promotes microbial dissemination, and other macrophages engulf the released bacteria....

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Bibliografiset tiedot
Päätekijät: Merlo, Andrea, Saverino, Daniele, Tenca, Claudya, Grossi, Carlo Enrico, Bruno, Silvia, Ciccone, Ermanno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2001
Aiheet:
Microbial Immunity and Vaccines
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC98730/
https://ncbi.nlm.nih.gov/pubmed/11553539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.10.6022-6029.2001
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