Cholera Toxin B Subunit as a Carrier Molecule Promotes Antigen Presentation and Increases CD40 and CD86 Expression on Antigen-Presenting Cells

Cholera toxin B subunit (CTB) is an efficient mucosal carrier molecule for the generation of mucosal antibody responses and/or induction of systemic T-cell tolerance to linked antigens. CTB binds with high affinity to GM1 ganglioside cell surface receptors. In this study, we evaluated how conjugatio...

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Bibliographische Detailangaben
Hauptverfasser: George-Chandy, Annie, Eriksson, Kristina, Lebens, Michael, Nordström, Inger, Schön, Emma, Holmgren, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98688/
https://ncbi.nlm.nih.gov/pubmed/11500448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5716-5725.2001
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