Oral tolerance induction by mucosal administration of cholera toxin B-coupled antigen involves T-cell proliferation in vivo and is not affected by depletion of CD25(+) T cells

Oral administration of antigens coupled to the B subunit of the cholera toxin (CTB) can dramatically reduce the amount of antigen needed for tolerance induction and has been used in several animal models to suppress conditions where the immune system overreacts to foreign and self-antigens. In this...

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Hlavní autoři: Chandy, Annie George, Hultkrantz, Susanne, Raghavan, Sukanya, Czerkinsky, Cecil, Lebens, Michael, Telemo, Esbjörn, Holmgren, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782302/
https://ncbi.nlm.nih.gov/pubmed/16827892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02368.x
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