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Oral tolerance induction by mucosal administration of cholera toxin B-coupled antigen involves T-cell proliferation in vivo and is not affected by depletion of CD25(+) T cells

Oral administration of antigens coupled to the B subunit of the cholera toxin (CTB) can dramatically reduce the amount of antigen needed for tolerance induction and has been used in several animal models to suppress conditions where the immune system overreacts to foreign and self-antigens. In this...

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Bibliografske podrobnosti
Main Authors: Chandy, Annie George, Hultkrantz, Susanne, Raghavan, Sukanya, Czerkinsky, Cecil, Lebens, Michael, Telemo, Esbjörn, Holmgren, Jan
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782302/
https://ncbi.nlm.nih.gov/pubmed/16827892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02368.x
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