Oral tolerance induction by mucosal administration of cholera toxin B-coupled antigen involves T-cell proliferation in vivo and is not affected by depletion of CD25(+) T cells

Oral administration of antigens coupled to the B subunit of the cholera toxin (CTB) can dramatically reduce the amount of antigen needed for tolerance induction and has been used in several animal models to suppress conditions where the immune system overreacts to foreign and self-antigens. In this...

Full description

Saved in:
Bibliographic Details
Main Authors: Chandy, Annie George, Hultkrantz, Susanne, Raghavan, Sukanya, Czerkinsky, Cecil, Lebens, Michael, Telemo, Esbjörn, Holmgren, Jan
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2006
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782302/
https://ncbi.nlm.nih.gov/pubmed/16827892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02368.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items