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Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans

The induction of immune responses to rectally administered recombinant cholera toxin B subunit (CTB) in humans was studied. Three immunizations induced high levels of CTB-specific antibody-secreting cells, particular of the immunoglobulin A isotype, in both rectum and peripheral blood. Antitoxin ant...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Jertborn, Marianne, Nordström, Inger, Kilander, Anders, Czerkinsky, Cecil, Holmgren, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11349086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.6.4125-4128.2001
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