Local and Systemic Immune Responses to Rectal Administration of Recombinant Cholera Toxin B Subunit in Humans

The induction of immune responses to rectally administered recombinant cholera toxin B subunit (CTB) in humans was studied. Three immunizations induced high levels of CTB-specific antibody-secreting cells, particular of the immunoglobulin A isotype, in both rectum and peripheral blood. Antitoxin ant...

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Bibliographische Detailangaben
Hauptverfasser: Jertborn, Marianne, Nordström, Inger, Kilander, Anders, Czerkinsky, Cecil, Holmgren, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98479/
https://ncbi.nlm.nih.gov/pubmed/11349086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.4125-4128.2001
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