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Differential effect of cholera toxin on CD45RA(+) and CD45RO(+) T cells: specific inhibition of cytokine production but not proliferation of human naive T cells

We have studied how cholera toxin (CT) and its non-toxic cell-binding B-subunit (CTB) affect the activation of pure human T cells in an anti-CD3-driven system. CT, as opposed to CTB, strongly suppressed the proliferative responses as well as cytokine production in CD4(+) and CD8(+) T cells. CT howev...

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Detalhes bibliográficos
Main Authors: Eriksson, K, Nordström, I, Czerkinsky, C, Holmgren, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905696/
https://ncbi.nlm.nih.gov/pubmed/10931143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01282.x
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