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Interleukin-6 Deficiency Influences Cytokine Expression in Susceptible BALB Mice Infected with Leishmania major but Does Not Alter the Outcome of Disease
Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (lesion size and parasite burden) in IL-6(−/−) and wild-type mice, but IL-6(−/−) mice expressed lower...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC98619/ https://ncbi.nlm.nih.gov/pubmed/11447205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.5189-5192.2001 |
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