Interleukin-6 Deficiency Influences Cytokine Expression in Susceptible BALB Mice Infected with Leishmania major but Does Not Alter the Outcome of Disease

Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (lesion size and parasite burden) in IL-6(−/−) and wild-type mice, but IL-6(−/−) mice expressed lower...

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Detalhes bibliográficos
Main Authors: Titus, Richard G., DeKrey, Gregory K., Morris, Robin V., Soares, Milena B. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98619/
https://ncbi.nlm.nih.gov/pubmed/11447205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.5189-5192.2001
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