Interleukin-6 Deficiency Influences Cytokine Expression in Susceptible BALB Mice Infected with Leishmania major but Does Not Alter the Outcome of Disease

Since interleukin-6 (IL-6) may promote Th2 responses, we infected BALB IL-6-deficient (IL-6(−/−)) mice with Leishmania major. There was not a significant difference between the courses of infection (lesion size and parasite burden) in IL-6(−/−) and wild-type mice, but IL-6(−/−) mice expressed lower...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Titus, Richard G., DeKrey, Gregory K., Morris, Robin V., Soares, Milena B. P.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Fungal and Parasitic Infections
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.8.5189-5192.2001
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