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Differential Regulation of the Interleukin-12 Receptor during the Innate Immune Response to Leishmania major

Previous studies have shown the central role of interleukin 12 (IL-12) in the development of resistance to Leishmania major infection in C3H mice. We now show that during the innate immune response the lymph node cells of L. major-infected C3H mice upregulate the IL-12 receptor on CD4(+), CD8(+), an...

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Autors principals: Jones, Douglas, Elloso, M. Merle, Showe, Louise, Williams, Donna, Trinchieri, Giorgio, Scott, Phillip
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC108425/
https://ncbi.nlm.nih.gov/pubmed/9673267
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