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Differential Regulation of the Interleukin-12 Receptor during the Innate Immune Response to Leishmania major

Previous studies have shown the central role of interleukin 12 (IL-12) in the development of resistance to Leishmania major infection in C3H mice. We now show that during the innate immune response the lymph node cells of L. major-infected C3H mice upregulate the IL-12 receptor on CD4(+), CD8(+), an...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Jones, Douglas, Elloso, M. Merle, Showe, Louise, Williams, Donna, Trinchieri, Giorgio, Scott, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108425/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3818-3824.1998
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